Cell-to-cell communication plays a cardinal role in the biology of multicellular organisms.H2O2 is an important cell-to-cell signaling molecule involved in the response of mammalian cells to wounding and other stimuli.We previously identified a signaling pathway that transmits wound-induced cell-to-cell H2O2 signals within minutes over long distanc
The Hypersensitive Response to Tomato leaf curl New Delhi virus Nuclear Shuttle Protein Is Inhibited by Transcriptional Activator Protein
The hypersensitive response (HR) is a common feature of plant disease resistance reactions and a type of programmed cell death (PCD).Many pathogens PWR REC Sofa with ADJ Headrest are able to modulate pathways involved in cell death.In contrast to animal viruses, inhibitors of PCD activity have not been identified for plant-infecting viruses.Previou
Novel strategy for oncogenic alteration-induced lipid metabolism reprogramming in pancreatic cancer
The pathogenesis of pancreatic cancer involves substantial metabolic reprogramming, resulting in abnormal proliferation of tumor cells.This tumorigenic reprogramming is often driven by genetic mutations, such as activating mutations of the KRAS oncogene and inactivating or deletions of the tumor suppressor genes SMAD4, CDKN2A, and TP53, which play